Question Replacing CuCl2 with sulphate?

MadHatter

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In the NaBH4 reduction of P2NP to amphetamine, can CuCl2 be substituted for CuSO4? Or do the sulphate ions interfere?
 

HerrHaber

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Confirmed, you must take into account the molarity of the aqueous solution and the water of crystalization which is 5 water molecules per CuSO4 molecule when talking about the blue crystals which are the more common form with a molar mass of 249,28 g/mole including the five moles of water in it. You should prepare the solution with the same molarity as the nitrate or chloride in the procedure.
 
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